Epigenetic sequencing
Epigenetics is emerging as a key tool for understanding the mechanistic underpinnings that regulate gene expression. Monitoring methylation, DNA accessibility, DNA-protein interactions, and non-coding small RNA functions can help to further understand the molecular landscape of cellular function, particularly when coupled with RNA-seq and DNA-seq.
Methods of interrogating these epigenetic factors are described in the technical notes and other resources below.
ChIP-seq libraries for transcription factors
Learn how researchers used our low-input ThruPLEX DNA-Seq kit to perform ChIP-seq with 10-fold less starting sample.
ChIP-seq libraries from single-stranded DNA
The ChIP Elute Kit and DNA SMART ChIP-seq kit are robust, reliable tools for low-input ChIP-seq applications.
Full-length small RNA libraries
The SMARTer smRNA-Seq Kit for Illumina allows for analysis of diverse small RNA species with high accuracy and sensitivity.
Methylated DNA-seq with MBD2
The EpiXplore Meth-Seq DNA Enrichment Kit provides a user-friendly solution for high-throughput analysis of DNA methylation patterns.
Profiling transcription factors with CUT&RUN sequencing
Learn how Dr. Karl Glastad of the University of Pennsylvania overcame the limits of ChIP-seq to identify the molecular determinants underpinning caste-differential gene expression in ants.
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