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Stem cell research

In stem cell research, new questions arise as rapidly as new discoveries are generated. Your innovative ideas have no boundaries when backed by our tools—cells, media, differentiation systems, and reagents. With over 15 years of stem cell experience behind our Cellartis brand, we test the boundaries of knowledge to facilitate your exploration of health and wellness.

Whether you want to derive and expand pluripotent cells, to tightly control (or prevent) differentiation, to edit your cells, or to differentiate them along a specific lineage, our products support your aim. At every step, our tools for reprogramming, culture, engineering, differentiation, and analysis will remove technical hurdles, allowing you to push your experiments forward.

Select your features below:

Cat. #

Product

Size

Price

License

Quantity

Details

Y40031

Cellartis® 2i mES/iPSC Culture Medium

200 mL

USD $352.00

Cellartis 2i mES/iPSC Culture Medium is a serum-free, defined cell culture medium for the establishment of mouse ES and iPS cell lines. This medium contains two selective small molecule inhibitors ('2i'), CHIR99021 and PD0325901, that act to eliminate differentiation-inducing signals from GSK3β and ERK/MEK, respectively, and promote cell proliferation.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Components

Y40011

Cellartis® 3i mES/iPSC Culture Medium

200 mL

USD $487.00

Cellartis 3i mES/iPSC Culture Medium is a serum-free, defined cell culture medium for the establishment, maintenance, and propagation of mouse embryonic stem (mES) cells. This medium contains three selective small molecule inhibitors (3i technology: ERK/MEK inhibitor, GSK3β inhibitor, and FGFR-TK inhibitor) that act to eliminate differentiation-inducing signals and promote cell proliferation, enabling the maintenance of the pluripotent ground state without the the need for additional stimulatory cytokines.

Notice to purchaser

Components

Y30017

Cellartis® DEF-CS™ 500 Basal Medium with Additives

500 mL

USD $478.00

License Statement

ID Number

C001

This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.

Cellartis DEF-CS 500 Basal Medium with Additives is a robust media for efficient expansion of human induced pluripotent stem (iPS) cells in a feeder-free and defined environment. This kit includes Cellartis DEF-CS 500 Basal Medium and Cellartis DEF-CS 500 Additives.

Notice to purchaser

Components

Y30012

Cellartis® DEF-CS™ 500 COAT-1

4 mL

USD $269.00

Cellartis DEF-CS 500 COAT-1 is a part of the Cellartis DEF-CS 500 Culture System, a defined culture system for efficient expansion of undifferentiated human pluripotent stem cells. In addition to the coating substrate, the complete System includes basal medium and additives.

Notice to purchaser

Components

Y30010

Cellartis® DEF-CS™ 500 Culture System

1 Kit

USD $583.00

License Statement

ID Number

C001

Cellartis DEF-CS 500 Culture System is a defined culture system for efficient expansion of undifferentiated human pluripotent stem cells. This kit includes basal medium, coating substrate, and additives.

Notice to purchaser

Components

Y30042

Cellartis® DEF-CS™ 500 Xeno-Free Additives

1 Kit

USD $189.00

Cellartis DEF-CS 500 Xeno-Free Additives kit is a part of the Cellartis DEF-CS 500 Xeno-Free Culture Medium, a pre-clinical grade, chemically defined culture medium that is free from human- and animal-derived components and is used for efficient expansion of undifferentiated human induced pluripotent stem cells.

Notice to purchaser

Components

Y30045

Cellartis® DEF-CS™ 500 Xeno-Free Culture Medium w/o Antibiotics

1 Kit

USD $386.00

Cellartis DEF-CS 500 Xeno-Free Culture Medium without Antibiotics is a pre-clinical grade, chemically defined culture medium that is free from human- and animal-derived components and is used for efficient expansion of undifferentiated human induced pluripotent stem cells. This kit includes basal medium and additives.

Notice to purchaser

Components

Y30071

Cellartis® DEF-CS™ 500 Xeno-Free GMP Grade Basal Medium

500 mL

Inquire for Quotation

Cellartis DEF-CS 500 Xeno-Free GMP Grade Basal Medium is a chemically defined basal media that is free from human- and animal-derived components and is used for efficient expansion of undifferentiated human induced pluripotent stem (iPS) cells. Cellartis DEF-CS 500 Xeno-Free GMP Grade Basal Medium is manufactured as a quality-assured product, in compliance with the "Guide to Good Manufacturing Practice for Medicinal Products" notifed by PIC/S.

Notice to purchaser

This product is to be used for research use only, including non-commercial manufacturing for clinical research. This product is not intended for humans or animals in-vivo applications. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Components

Y10040

Cellartis® Definitive Endoderm Cells (from ChiPSC18)

1 Vial

USD $653.00

License Statement

ID Number
C007	This product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) (“Takara”) under a license from ViaCyte Inc. (“ViaCyte”). This product is covered by one or more claims of patents owned by ViaCyte, including WO2005063971, WO2006017134, WO2006071911, WO2005116073 and WO200616999, and their foreign counterparts. The use of this product is strictly limited to purchaser's own internal research. Purchaser has no right to use this product or its components in humans for any purposes including but not limited to diagnostics, therapeutics, or clinical trials. Purchaser has no right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact Takara. No express or implied license is granted to the purchaser.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L67	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 9,938,585 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This Product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc. No express or implied license is granted to the purchaser. "Product" means the differentiated cells manufactured and sold by Takara Bio Inc. "Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser's contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes: With the exemption for academic and non-commercial clinical research done by non-profit institutions; 1) Administration of this Product to humans. 2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases. 3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc. Purchaser may use this Product for its own Internal research purposes. Purchaser shall not use the Products for its commercial purposes. Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party's Internal research purposes.

Cellartis Definitive Endoderm Cells (from ChiPSC18) are human definitive endoderm (DE) cells derived from the human induced pluripotent stem (iPS) cell line ChiPSC18. The cells have been differentiated to definitive endoderm cells in vitro, dissociated to a cell suspension, and frozen in vials.

Notice to purchaser

Components

Y30035

Cellartis® Definitive Endoderm Differentiation Kit with DEF-CS™ Culture System

1 Kit

USD $541.00

License Statement

ID Number

C001

C007

This product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) (“Takara”) under a license from ViaCyte Inc. (“ViaCyte”). This product is covered by one or more claims of patents owned by ViaCyte, including WO2005063971, WO2006017134, WO2006071911, WO2005116073 and WO200616999, and their foreign counterparts. The use of this product is strictly limited to purchaser's own internal research. Purchaser has no right to use this product or its components in humans for any purposes including but not limited to diagnostics, therapeutics, or clinical trials. Purchaser has no right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact Takara. No express or implied license is granted to the purchaser.

The Cellartis Definitive Endoderm Differentiation Kit contains complete media and a ready-to-use coating for the differentiation of human induced pluripotent stem (iPS) cells to definitive endoderm (DE) cells in 2D culture. The complete Cellartis Definitive Endoderm Differentiation Kit with DEF-CS Culture System contains the Cellartis Definitive Endoderm Differentiation Kit plus the Cellartis DEF-CS 100 Culture System, which is used to culture undifferentiated human iPS cells.

Notice to purchaser

Components

Y10133

Cellartis® Enhanced hiPS-HEP v2 (from ChiPSC12) Kit

1 Kit

USD $2390.00

License Statement

ID Number

C005

This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.

L67

This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 9,938,585 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein.

This Product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc.

No express or implied license is granted to the purchaser.

"Product" means the differentiated cells manufactured and sold by Takara Bio Inc.

"Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser's contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes:

With the exemption for academic and non-commercial clinical research done by non-profit institutions;

1) Administration of this Product to humans.

2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases.

3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc.

Purchaser may use this Product for its own Internal research purposes.

Purchaser shall not use the Products for its commercial purposes.

Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party's Internal research purposes.

The Cellartis Enhanced hiPS-HEP v2 (from ChiPSC12) Kit is an optimized, complete system for the long-term maintenance of Cellartis Enhanced hiPS-HEP (from ChiPSC12) cells. These cells, included in the kit, are cryopreserved human hepatocytes derived from the Cellartis human induced pluripotent stem cell line 12 (ChiPSC12). The Cellartis Enhanced hiPS-HEP v2 (from ChiPSC12) Kit also contains a kit for thawing and plating of the cells and a long-term maintenance medium suitable for up to 19 days of cell culture.

Notice to purchaser

Components

Y10134

Cellartis® Enhanced hiPS-HEP v2 (from ChiPSC18) Kit

1 Kit

USD $2390.00

License Statement

ID Number

C005

L67

The Cellartis Enhanced hiPS-HEP v2 (from ChiPSC18) Kit is an optimized, complete system for the long-term maintenance of Cellartis Enhanced hiPS-HEP (from ChiPSC18) cells. These cells, included in the kit, are cryopreserved human hepatocytes derived from the Cellartis human induced pluripotent stem cell line 18 (ChiPSC18). The Cellartis Enhanced hiPS-HEP v2 (from ChiPSC18) Kit also contains a kit for thawing and plating of the cells and a long-term maintenance medium suitable for up to 19 days of cell culture.

Notice to purchaser

Components

Y30050

Cellartis® Hepatocyte Differentiation Kit

1 Kit

USD $906.00

Cellartis Hepatocyte Differentiation Kit contains complete media and ready-to-use coating for the differentiation of definitive endoderm (DE) cells to hepatocyte cells in 2D culture.

Notice to purchaser

Components

Y30051

Cellartis® Hepatocyte Maintenance Medium

100 mL

USD $292.00

Cellartis Hepatocyte Maintenance Medium are used for prolonged maintenance of hepatocyte cells in 2D culture, derived using Cellartis Hepatocyte Differentiation Kit (Cat. No. Y30050) or Cellartis iPS Cell to Hepatocyte Differentiation System (Cat. No. Y30055).

Notice to purchaser

Components

Y10108

Cellartis® hiPS Beta Cell Media Kit

1 Kit

USD $1027.00

The Cellartis hiPS Beta Cell Media Kit is a complete system for the maintenance of beta cells provided within the Cellartis hiPS Directed Differentiation to Beta Cells Services (Cat. Nos. Y60230, Y60232, and Y60234). One Cellartis hiPS Beta Cell Media Kit is enough to culture one vial of beta cells. The Cellartis hiPS Beta Cell Media Kit contains a supplement, a coating substrate, and two types of basal media.

Notice to purchaser

Components

Y10100

Cellartis® hiPS Beta Cells (from ChiPSC12) Kit

1 Kit

USD $2260.00

License Statement

ID Number

C005

L67

Cellartis hiPS Beta Cells (from ChiPSC12), derived from human induced pluripotent stem cells, are ideal for diabetes modeling and drug discovery.

Notice to purchaser

Components

Y10106

Cellartis® hiPS Beta Cells (from ChiPSC22) Kit

1 Kit

USD $2260.00

License Statement

ID Number

C005

L67

Cellartis hiPS Beta Cells (from ChiPSC22), derived from human induced pluripotent stem cells, are ideal for diabetes modeling and drug discovery.

Notice to purchaser

Components

Y00025

Cellartis® Human ES Cell Line 121 (SA121) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C004	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by GE Healthcare UK Limited (“GE”). This product and its use are covered by one or more claims of U.S. Patent No. 9,074,181 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C018	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human ES Cell Line license agreement to us. For details please contact licensing@takarabio.com. A copy of the Cellartis® Human ES Cell Line 121 (SA121) Kit product License Agreement can be found by clicking here.

Cellartis human embryonic cell line kits contain ethically derived cells that are banked and characterized per the highest industry standards.

Notice to purchaser

Components

Y00065

Cellartis® Human ES Cell Line 167 (SA167) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C004	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by GE Healthcare UK Limited (“GE”). This product and its use are covered by one or more claims of U.S. Patent No. 9,074,181 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C018	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human ES Cell Line license agreement to us. For details please contact licensing@takarabio.com. A copy of the Cellartis® Human ES Cell Line 167 (SA167) Kit product License Agreement can be found by clicking here.

Cellartis human embryonic cell line kits contain ethically derived cells that are banked and characterized per the highest industry standards.

Notice to purchaser

Components

Y00105

Cellartis® Human ES Cell Line 181 (SA181) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C004	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by GE Healthcare UK Limited (“GE”). This product and its use are covered by one or more claims of U.S. Patent No. 9,074,181 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C018	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human ES Cell Line license agreement to us. For details please contact licensing@takarabio.com. A copy of the Cellartis® Human ES Cell Line 181 (SA181) Kit product License Agreement can be found by clicking here.

Cellartis human embryonic cell line kits contain ethically derived cells that are banked and characterized per the highest industry standards.

Notice to purchaser

Components

Y00145

Cellartis® Human ES Cell Line 461 (SA461) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C004	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by GE Healthcare UK Limited (“GE”). This product and its use are covered by one or more claims of U.S. Patent No. 9,074,181 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C018	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human ES Cell Line license agreement to us. For details please contact licensing@takarabio.com. A copy of the Cellartis® Human ES Cell Line 461 (SA461) Kit product License Agreement can be found by clicking here.

Cellartis human embryonic cell line kits contain ethically derived cells that are banked and characterized per the highest industry standards.

Notice to purchaser

Components

Y00285

Cellartis® Human iPS Cell Line 12 (ChiPSC12) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 12 (ChiPSC12) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 12 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y00305

Cellartis® Human iPS Cell Line 18 (ChiPSC18) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 18 (ChiPSC18) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 18 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y00325

Cellartis® Human iPS Cell Line 22 (ChiPSC22) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 22 (ChiPSC22) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 22 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y00275

Cellartis® Human iPS Cell Line 7 (ChiPSC7) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 7 (ChiPSC7) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 7 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y50035

Cellartis® Intestinal Epithelial Cells (from ChiPSC18) Kit

1 Kit

Inquire for Quotation

License Statement

ID Number
L67	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141, 9,714,433, and 9,938,585 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This Product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) based on a patent license from iPS Academia Japan, Inc. No express or implied license is granted to the purchaser. "Product" means the differentiated cells manufactured and sold by Takara Bio Inc. "Internal research purpose" means the use of this Product as a tool of internal research for the sole benefit of the purchaser or purchaser's contract research customer, (including screening of compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use), provided, however, that the following activities using this Product are strictly prohibited and expressly excluded from Internal research purposes: With the exemption for academic and non-commercial clinical research done by non-profit institutions; 1) Administration of this Product to humans. 2) Use of this Product for the diagnostic testing, prevention, or treatment of human and/or animal diseases. 3) Use of this Product in studies involving administration to humans for cell therapy, regenerative medicine etc. Purchaser may use this Product for its own Internal research purposes. Purchaser shall not use the Products for its commercial purposes. Notwithstanding the foregoing, the purchaser of this Product may provide third parties with contract research services by using this Product only for such third party's Internal research purposes.
C007	This product is manufactured and sold by Takara Bio Inc. and/or its affiliate(s) (“Takara”) under a license from ViaCyte Inc. (“ViaCyte”). This product is covered by one or more claims of patents owned by ViaCyte, including WO2005063971, WO2006017134, WO2006071911, WO2005116073 and WO200616999, and their foreign counterparts. The use of this product is strictly limited to purchaser's own internal research. Purchaser has no right to use this product or its components in humans for any purposes including but not limited to diagnostics, therapeutics, or clinical trials. Purchaser has no right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact Takara. No express or implied license is granted to the purchaser.
L72	This product is manufactured and sold by Takara Bio Inc. based on a license to Cellectis SA. The use of this product is strictly limited to purchaser's own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L79	This product is covered by the claims of pending applications WO2020/262492.

Note: This is a made-to-order product with a lead time and a minimum order quantity. Please inquire.

Cellartis Intestinal Epithelial Cells (from ChiPSC18) are small intestinal epithelial cells derived from human induced pluripotent stem (hiPS) cells. This product includes the following items: one frozen vial of Cellartis Intestinal Epithelial Cells (from ChiPSC18) and one Cellartis IEC Maturation Kit.

Notice to purchaser

Components

Y30055

Cellartis® iPS Cell to Hepatocyte Differentiation System

1 Kit

USD $1449.00

License Statement

ID Number

C007

C001

The Cellartis iPS Cell to Hepatocyte Differentiation System is a complete system for differentiation of human induced pluripotent stem (iPS) cells to hepatocytes via definitive endoderm (DE). This kit includes the Cellartis DEF-CS Culture System for expansion of undifferentiated iPS cells, the Cellartis Definitive Endoderm Differentiation Kit for differentiation to DE cells, and the Cellartis Hepatocyte Differentiation Kit for subsequent differentiation to hepatocytes.

Notice to purchaser

Components

Required Products

Cat. #	Product	Size	Price	License	Quantity	Details
Y30051	Cellartis® Hepatocyte Maintenance Medium	100 mL	USD $292.00
Cellartis Hepatocyte Maintenance Medium are used for prolonged maintenance of hepatocyte cells in 2D culture, derived using Cellartis Hepatocyte Differentiation Kit (Cat. No. Y30050) or Cellartis iPS Cell to Hepatocyte Differentiation System (Cat. No. Y30055). Documents Components

Y50200

Cellartis® MSC Xeno-Free Culture Medium

Each

USD $571.00

Cellartis MSC Xeno-Free Culture Medium is suitable for the maintenance and expansion of human mesenchymal stem cells (MSC) from bone marrow, adipose tissue, or umbilical cord—without plate coating reagents. However, coating cell culture vessels with human fibronectin can further promote proliferation. This xeno-free medium is ideal for cell therapy research applications such as bone/cartilage diseases, bone marrow transplants/GVHD, cardiovascular disease, autoimmune disease, liver disease, and cancer.

Notice to purchaser

Components

Y50205

Cellartis® MSC Xeno-Free Culture Medium (w/o Phenol Red)

500 mL

USD $571.00

Cellartis MSC Xeno-Free Culture Medium (w/o Phenol Red) is a xeno-free medium suitable for human MSC culture. It does not contain components, such as BSA, etc., that are derived from non-human species. Furthermore, it enables maintenance of MSC proliferation and pluripotency without plate coating reagents.

Notice to purchaser

Components

Y50210

Cellartis® MSC Xeno-Free GMP Grade Culture Medium

Each

USD $742.00

Cellartis MSC Xeno-Free GMP Grade Culture Medium is a xeno-free medium suitable for human MSC culture. It does not contain components, such as BSA, etc., that are derived from non-human species and is manufactured as a quality-assured product, in compliance with GMP guidelines of PIC/S (Pharmaceutical Inspection Convention and Pharmaceutical Inspection Co-operation Scheme). Furthermore, it enables maintenance of MSC proliferation and pluripotency without plate-coating reagents.

Notice to purchaser

Components

Y20020

Cellartis® Power™ Primary HEP Medium

250 mL

USD $521.00

Cellartis Power Primary HEP Medium is specially formulated to enable the long-term maintenance—cells are viable and maintain functionality for four weeks—of cryopreserved, plateable human primary hepatocytes in conventional 2D cultures. This medium further simplifies culturing of hepatocytes with a weekend-free feeding schedule.

Notice to purchaser

Components

7246

Human Mitochondrial DNA (mtDNA) Monitoring Primer Set

50 Rxns

USD $354.00

Human Mitochondrial DNA (mtDNA) Monitoring Primer Set is designed to quantify the relative number of copies of human mitochondrial DNA (mtDNA) by real-time PCR, using nuclear DNA (nDNA) content as a standard. This set contains primer pairs for the amplification of four regions: two primer pairs for the detection of mtDNA and two primer pairs for the detection of nDNA. Each primer is specifically designed and will not amplify pseudogenes. As the primers are human-specific and will not amplify DNA from mice, human mtDNA content can be monitored in iPS cells or other cells cultured with feeder cells of mouse origin. Using the four primer pairs in this set for real-time PCR, relative quantification of mtDNA is determined from the difference in Ct values for mtDNA and nDNA. This product provides a simple method for monitoring changes in the mtDNA copy number as mtDNA has been reported to increase during differentiation of pluripotent cells, such as iPS cells, into hepatic cells. The primer pairs in this set are compatible with Terra qPCR Direct TB Green Premix (Cat. # 638319) and TB Green Premix Ex Taq II (Tli RNase H Plus) (Cat. # RR820A/B).

Notice to purchaser

Components

T303

iMatrix-511

2 x 175 ug

USD $763.00

Laminin-511 is well known to bind to integrin α6ß1, which is located on the cell surface. iMatrix-511 is a recombinant fragment of laminin-511 which acts as a substrate for stem cell culture media for ESCs and iPSCs. iMatrix-511 is chemically defined, animal-free, and xeno-free.

Notice to purchaser

T304

iMatrix-511

6 x 175 ug

USD $1823.00

Notice to purchaser

RR290

Mouse Feeder Cell Quantification Kit

100 Rxns

USD $825.00

The Mouse Feeder Cell Quantification Kit is designed to facilitate highly sensitive detection and quantification of genomic DNA derived from residual mouse feeder cells using real-time PCR to analyze genomic DNA extracted from stem cell cultures (e.g., hESC, hiPSC). The kit includes primers for real-time PCR that were designed to detect a mouse mitochondrial (mt) DNA sequence, allowing detection of mouse feeder cells with high sensitivity. The copy number of cellular mtDNA is known to vary depending on cell type, cell line, and differentiation state, and there is a possibility of fluctuation betweenmouse feeder cell lots. The primer set for quantification of mouse mtDNA copy number included in this kit can be used for lot-to-lot correction of mouse feeder cells.

Notice to purchaser

Components

Y40002

NDiff® 227

500 mL

USD $396.00

NDiff 227 is a proprietary, defined, serum-free medium for the neural differentiation of mouse ES cells in adherent monolayer culture conditions. NDiff 227 has also been shown to support the serum-free, feeder-free culture of mouse ES cells. More recently, 227-like medium supplemented with growth factors has also been used to successfully maintain feeder-free human ES cells in culture. When supplemented with FGF, serum-free 227 also generates Anterior Definitive Endoderm (ADE) precursors from mouse ES cells, which can then be differentiated into liver and pancreas with enhanced efficiency.

Notice to purchaser

Components

MK430

Osteoblast-Inducer Reagent (for animal cell)

500 mL

USD $315.00

This product contains a set of osteoblast-inducer reagents, including hydrocortisone, β-glycerophosphate, and ascorbic acid. These reagents induce the efficient differentiation of bone marrow-derived cells and adipose-derived stem cells (mesenchymal stem cells) into osteoblasts when added to culture medium.

Notice to purchaser

Components

631965

Pluripotency Check PCR Kit

Each

USD $788.00

The Pluripotency Check PCR Kit can be used to validate the pluripotent status (ability to differentiate into specialized cells of all three germ layers) of your stem cell culture. It includes 16 forward and reverse primer mixes, based on nine genes expressed in pluripotent stem cells and two control genes, plus the reagents necessary for RNA extraction, first-strand cDNA synthesis, and PCR.

Notice to purchaser

Components

631966

Pluripotency Check PCR Primer Set

16 x 25 Rxns

USD $494.00

Validating the pluripotent status (ability to differentiate into specialized cells of all three germ layers) of your culture is a critical step in stem cell research. The Pluripotency Check PCR Primer Set consists of 16 forward and reverse primer mixes, based on nine genes expressed in pluripotent stem cells, plus two control genes.

Notice to purchaser

Components

Y40001

RHB-A®

500 mL

USD $357.00

RHB-A, supplemented with Epidermal Growth Factor (EGF) and Fibroblast Growth Factor-2 (FGF-2), enables the maintenance and continual expansion of symmetrically-dividing NS cells in defined, serum-free adherent culture. In growth factor supplemented RHB-A, NS cells have been demonstrated to retain their neurogenic capacity for over 100 generations, with full maintenance of diploid karyotype. RHB-A in the presence of EGF and FGF-2 also supports the derivation of clonogenic NS cell lines. Culture of adherent NS cells in RHB-A with sequential growth factor withdrawal leads to differentiation into functional neurons. RHB-A supplemented with EGF and FGF-2 has recently been used for the propagation of glioblastoma stem cell lines.

Notice to purchaser

Components

*You must be logged in to a Purchasing Account in order to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@takarabio.com.

Takara Bio USA, Inc.
United States/Canada: +1.800.662.2566 • Asia Pacific: +1.650.919.7300 • Europe: +33.(0)1.3904.6880 • Japan: +81.(0)77.565.6999
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. © 2024 Takara Bio Inc. All Rights Reserved. All trademarks are the property of Takara Bio Inc. or its affiliate(s) in the U.S. and/or other countries or their respective owners. Certain trademarks may not be registered in all jurisdictions. Additional product, intellectual property, and restricted use information is available at takarabio.com.

Stem cell research

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Y40031: Cellartis 2i mES/iPSC Culture Medium

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Cellartis 3i mES/iPSC Culture Medium maintains mouse ES cells in a homogeneous, undifferentiated state.

Comparison of chimeric rates in mouse lines established with Cellartis 3i mES/iPSC Culture Medium or conventional medium

Y40011: Cellartis 3i mES/iPSC Culture Medium

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Y30017: Cellartis DEF-CS 500 Basal Medium with Additives

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Y30012: Cellartis DEF-CS 500 COAT-1

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Expansion potential of a characterized working bank of human induced pluripotent stem (iPS) cells in the Cellartis DEF-CS Culture System

Robust growth of human induced pluripotent stem (iPS) cells in the Cellartis DEF-CS Culture System

Human induced pluripotent stem cells (iPS) cells grown in the Cellartis DEF-CS Culture System have the highest proportion and intensity of markers of pluripotency

Human iPS cells grown in the Cellartis DEF-CS Culture System look different from those grown with traditional aggregate culture techniques

Human induced pluripotent stem (iPS) cells cultured long-term in the Cellartis DEF-CS Culture System retain a normal karyotype

Human induced pluripotent stem (iPS) cells can be passaged as single cells in the Cellartis DEF-CS Culture System

Human pluripotent stem cells remain undifferentiated when cultured in the Cellartis DEF-CS Culture System

Y30010: Cellartis DEF-CS 500 Culture System

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Y30042: Cellartis DEF-CS 500 Xeno-Free Additives

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Y30045: Cellartis DEF-CS 500 Xeno-Free Culture Medium w/o Antibiotics

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The International Society for Pharmaceutical Engineering selected Takara’s Center for Gene and Cell Processing as the winner of its 2016 Facility of the Year Award (in the facility integration category)

Y30071: Cellartis DEF-CS 500 Xeno-Free GMP Grade Basal Medium

Notice to purchaser

Using the Cellartis Definitive Endoderm Differentiation Kit, cells from the human induced pluripotent stem (hiPS) cell line 18 (ChiPSC18) were differentiated into Definitive Endoderm (DE) cells

Immunocytochemistry of Cellartis Definitive Endoderm Cells (from ChiPSC18)

Notice to purchaser

mRNA expression profiles of definitive endoderm cells being generated from two hiPS cell lines (ChiPSC18 and P11025) using the Cellartis Definitive Endoderm Differentiation Kit with DEF-CS Culture Medium

Y30035: Cellartis Definitive Endoderm Differentiation Kit with DEF-CS Culture System

Notice to purchaser

Cellartis human induced pluripotent stem (iPS) cell-derived hepatocytes are a long-lasting, reliable liver disease model.

CYP450 activity is stable in enhanced hiPS-HEP cells over 21 days.

Notice to purchaser

Cellartis human induced pluripotent stem (iPS) cell-derived hepatocytes are a long-lasting, reliable liver disease model.

CYP450 activity is stable in enhanced hiPS-HEP cells over 21 days.

Albumin is present in enhanced hiPS-HEP cells through 20 days in culture.

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Definitive endoderm (DE) cells were differentiated into hepatocytes using the Cellartis Hepatocyte Differentiation Kit

Y30050: Cellartis Hepatocyte Differentiation Kit

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Donor information and HLA typification data.

Cellartis hiPS Beta Cells (from ChiPSC12) were exposed to incretin (100 nM GLP-1 or 100 nM exenatide) for 45 min in 5.5 mM glucose.

Human iPS cell-derived beta cells synthesize and secret insulin.

Cellartis beta cells were fixed 14 days post-thaw and co-stained for C-peptide (green) and MAFA (red).

Notice to purchaser

Donor information and HLA typification data.

Human iPS cell-derived beta cells synthesize and secret insulin.

Cellartis beta cells were fixed 14 days post-thaw and co-stained for C-peptide (green) and MAFA (red).

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Characteristics of Cellartis human iPS cells

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Characteristics of Cellartis human iPS cells

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Characteristics of Cellartis human iPS cells

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Characteristics of Cellartis human iPS cells

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Components of the Cellartis Intestinal Epithelial Cells (from ChIPSC18) Kit

Immunostaining of tight junction protein ZO-1

Expression of the intestinal epithelial markers villin and CDX2

Expression of drug metabolizing enzyme CYP3A4 and drug transporter PEPT1 mRNAs

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Immunocytochemistry analysis of hepatocyte differentiation

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Cellartis xeno-free MSC medium: robust proliferation even without coating

Cellartis xeno-free MSC medium maintains healthy MSC phenotype

Cellartis xeno-free MSC medium maintains MSC multilinear differentiation ability

No numerical or structural abnormalities identified in hMSC cultured in Cellartis MSC Xeno-Free Culture Medium

Healthy morphology and growth kinetics of hMSCs cultured in Cellartis MSC Xeno-Free Culture Medium