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Primary antibodies and ELISAs by research area

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Influenza detection and typing: Human influenza virus antibodies

The influenza virus is classified into three groups, A, B and C, based on key differences in the viral nuclear protein (NP). The basic structure of the influenza virus may be seen by clicking on the Images and Data tab below. Influenza virus particles contain head and stem regions that play vital roles in infection: The viral head region contains a receptor domain that binds the host cell, while the viral stem region carries a specific amino acid sequence that is necessary for the fusion of the virus with its host cell.

Influenza virus is further classified into subtypes based on its neuraminidase (NA) and haemagglutinin (HA) differences, both of which are key viral surface glycoproteins. Viral nuclear and glycoproteins are both targeted by human influenza virus antibodies in the process of influenza detection and typing. Currently, several major influenza epidemics have been attributed to influenza A and influenza B, or more specifically influenza A subtype H3 and influenza B subtype H1. These influenza H1N1 and H3N2 subtypes are well-known to result in severe febrile illness.

Cat. # Product Size Price License Quantity Details
M149 Polyclonal Antibody to Human Influenza A, B (Rabbit Polyclonal) 0.4 mg USD $333.00

Influenza virus is classified into three groups (A, B, and C). Clinically prevalent types of Influenza virus are H1, H3 and B strain. Influenza virus is further classified into subtypes based on variances in Neuraminidase (NA) and Haemagglutinin (HA) that are the surface glycoprotein of the virus. H1N1 subtype and H3N2 subtype are known to cause severe febrile illness. An influenza virus particle consists of a head region and a stem region. The head region has a receptor domain and the stem region contains a region required for fusion between the virus and the target cell. Takara offers several influenza antibodies that are useful for various viral detection and typing methods, as well as neutralization assays. These antibodies are for research use only.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components
M148 Monoclonal Anti-Human Influenza B (Clone 9D6) 0.1 mg USD $418.00

Influenza virus is classified into three groups (A, B, and C). Clinically prevalent types of Influenza virus are H1, H3 and B strain. Influenza virus is further classified into subtypes based on variances in Neuraminidase (NA) and Haemagglutinin (HA) that are the surface glycoprotein of the virus. H1N1 subtype and H3N2 subtype are known to cause severe febrile illness. An influenza virus particle consists of a head region and a stem region. The head region has a receptor domain and the stem region contains a region required for fusion between the virus and the target cell. Takara offers several influenza antibodies that are useful for various viral detection and typing methods, as well as neutralization assays. These antibodies are for research use only.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components Image Data
M147 Monoclonal Anti-Influenza A (H1, H2, H3) (Clone C111) 0.1 mg USD $421.00

Influenza virus is classified into three groups (A, B, and C). Clinically prevalent types of Influenza virus are H1, H3 and B strain. Influenza virus is further classified into subtypes based on variances in Neuraminidase (NA) and Haemagglutinin (HA) that are the surface glycoprotein of the virus. H1N1 subtype and H3N2 subtype are known to cause severe febrile illness. An influenza virus particle consists of a head region and a stem region. The head region has a receptor domain and the stem region contains a region required for fusion between the virus and the target cell. Takara offers several influenza antibodies that are useful for various viral detection and typing methods, as well as neutralization assays. These antibodies are for research use only.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components Image Data
M146 Monoclonal Anti-Human Influenza A (H3N2) (Clone F49) 0.1 mg USD $418.00

Influenza virus is classified into three groups (A, B, and C). Clinically prevalent types of Influenza virus are H1, H3 and B strain. Influenza virus is further classified into subtypes based on variances in Neuraminidase (NA) and Haemagglutinin (HA) that are the surface glycoprotein of the virus. H1N1 subtype and H3N2 subtype are known to cause severe febrile illness. An influenza virus particle consists of a head region and a stem region. The head region has a receptor domain and the stem region contains a region required for fusion between the virus and the target cell. Takara offers several influenza antibodies that are useful for various viral detection and typing methods, as well as neutralization assays. These antibodies are for research use only.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components Image Data
M145 Monoclonal Anti-Human Influenza A (H1N1, H2N2) (Clone C179) 0.1 mg USD $418.00

Influenza virus is classified into three groups (A, B, and C). Clinically prevalent types of Influenza virus are H1, H3 and B strain. Influenza virus is further classified into subtypes based on variances in Neuraminidase (NA) and Haemagglutinin (HA) that are the surface glycoprotein of the virus. H1N1 subtype and H3N2 subtype are known to cause severe febrile illness. An influenza virus particle consists of a head region and a stem region. The head region has a receptor domain and the stem region contains a region required for fusion between the virus and the target cell. Takara offers several influenza antibodies that are useful for various viral detection and typing methods, as well as neutralization assays. These antibodies are for research use only.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Documents Components Image Data Resources

More Information

Applications

  • Clones C179, F49, C111 and 9D6 can be used for influenza virus detection and typing
  • Human Influenza Virus Antibodies can be used for detection of both Influenza A and B viruses
  • Monoclonal C179, F49, C111, 9D6 and the polyclonal antibody can be used for immunohistochemistry via PAP (peroxidade-antiperoxidase) staining
  • Clone C179 can be used for the neutralization activity studies of influenza viruses H1N1 and H2N2
  • Clone C179 can be used in experiments that prevent influenza infection of animals
  • Anti-influenza antibody (Clones C111 and 9D6) can be used for Western blot analysis

Source

Clone Target Target host Sub-
class		 Dilution
C179 Influenza A virus A/Okuda/57 strain (H2N2) BALB/c mouse IgG2a 1:2,000
F49 Influenza A virus A2/Aichi2/68/ strain (H3N2) BALB/c mouse IgG1 1:2,000
C111 Influenza A virus A/Okuda/57 strain (H2N2) BALB/c mouse IgG2a 1:2,000
9D6 Influenza B virus B/Nagasaki/1/87 strain BALB/c mouse IgG1 1:2,000
Polyclonal Vaccine mixture of influenza
A/Peking/262/95(H1N1),
A/Wuhan/395/95(H3N2), B/Mie/1/93 and
B/Guandong/05/94		 Rabbit

 

Notes

For research use only. Not for clinical diagnostics.

Form

Lyophilized

  • Monoclonal (Cat. #M145, M146, M147, M148)
    • Dissolve in 50 µl of distilled water (final conc.: 2.0 mg/ml, not containing any preservative)
  • Polyclonal (Cat. #M149)
    • Dissolve in 200 µl of distilled water (final conc.: 2.0 mg/ml, not containing any preservative)

Specificity

Anti-Human Influenza A (H1N1, H2N2)

  • This antibody specifically recognizes the highly conserved HA stem epitope in H1N1 and H2N2 viruses.

  • No cross-reactivity with HA in the influenza A H3N2 subtype.

  • Refer to the monoclonal antibody titer table for viral titer information.

  • This antibody has H1N1 and H2N2 virus neutralization activity.

  • This antibody does not affect viral HA inhibition tests.

Anti-Human Influenza A (H3N2)

  • This antibody specifically recognizes the HA stem epitope in the H3N2 virus.

  • This antibody does not cross react with HA in H1N1 and H2N2 subtypes of Influenza A virus.

  • Refer to the monoclonal antibody titer table for viral titer information.

  • This antibody cross-reacts A/duck/Czechoslovakia/1/56 (H4N6) and A/chicken/Germany "N"/49 (H10N7) in addition to human influenza virus.

  • This antibody has no effect on haemagglutination inhibition test for all subtypes of virus.

Anti-Human Influenza A (H1, H2, H3)

  • This antibody specifically recognizes the membrane protein epitope in all subtypes of Influenza A virus, including H1N1, H2N2 and H3N2.

  • Refer to the monoclonal antibody titer table for viral titer information.

Anti-Human Influenza B

  • This antibody specifically recognizes the nuclear protein (NP) epitope of Influenza B virus.

  • Refer to the monoclonal antibody titer table for viral titer information.

Polyclonal antibody to Human Influenza A, B

  • Antibody reacts with epitopes of Influenza A/PR/8/34 (H1N1), A/Aichi/2/68 (H3N2) and B/Nagaski/1/87.

  • Antibody is estimated to react equally with both Influenza A and B virus.

Additional product information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

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