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Stem cell research

Human induced pluripotent stem cells

Cellartis Human iPS Cell Line Kits contain human induced pluripotent stem (iPS) cells that are banked and characterized according to the highest industry standards, along with a starter set for the Cellartis DEF-CS Culture System. The iPS cells are adapted to the Cellartis DEF-CS Culture System, an easy-to-use, complete culture system for efficient iPS-cell expansion in a feeder-free, defined environment. With this system, cells are maintained in an undifferentiated state with virtually no background differentiation, eliminating the need for cell selection. The highly reproducible nature of the DEF-CS system coupled with the stable high growth rate of these stem cell lines is ideal for mass production of cells. We currently offer multiple cell lines derived from different donors (see product image).

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Y00325

Cellartis® Human iPS Cell Line 22 (ChiPSC22) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 22 (ChiPSC22) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 22 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Our products are to be used for Research Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval.

Components

Y00305

Cellartis® Human iPS Cell Line 18 (ChiPSC18) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 18 (ChiPSC18) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 18 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y00285

Cellartis® Human iPS Cell Line 12 (ChiPSC12) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 12 (ChiPSC12) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 12 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Y00275

Cellartis® Human iPS Cell Line 7 (ChiPSC7) Kit

1 Kit

USD $1650.00

License Statement

ID Number
C001	This product is manufactured and sold by Takara Bio Europe SAS based on a commercial license to certain intellectual property rights held by Wisconsin Alumni Research Foundation (“WARF”). This product is covered by one or more claims of U.S. Patent No. 7,514,260 and its foreign counterparts. The purchase of this product conveys to the buyer the non-transferable right to use the product for its intended use, strictly limited to purchaser’s own internal research. No other express or implied license is granted to the purchaser. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us.
C005	This product is manufactured and sold by Takara Bio Europe SAS based on a license to Cellectis SA. The use of this product is strictly limited to purchaser’s own internal research, including basic research, drug discovery research up to and including IND-enabling preclinical toxicological studies or equivalents thereof, excluding any use in the T-cell field. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser.
L44	This product is covered by one or more claims of the issued patents and pending patent applications: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187, 8,211,697, 8,257,941, 8,278,104, 8,530,238, 8,900,871, 8,927,277, 8,951,801, 9,213,999, 9,404,124, 9,499,797, 9,677,141 and 9,714,433, and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein. This product is manufactured and sold by Takara Bio Inc. based on a patent license from iPS Academia Japan, Inc. The use of this product is strictly limited to purchaser’s own internal research. Purchaser cannot have any right to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchase does not include any right to resell or transfer this product to a third party regardless of whether or not compensation is received. The use of iPSCs generated by this product is not allowed for the purposes of the intended use as described below: 1) Creation of a human clone through transplantation of iPSCs-derived embryos into human or animal individuals, 2) iPSCs transplantation into human embryos, 3) iPSCs transplantation into human fetuses, and 4) Production of human embryos using iPSCs-derived germ cells. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. Any use of this product for Commercial Purposes requires a patent license from iPS Academia Japan, Inc. "Commercial Purposes" means at least one of following activities including the use of iPSCs generated by this product: 1) Use for manufacture of related products for sale including but not limited to culture medium or equipment, 2) Use in order to provide a service to a third party (including use of the differentiated cells from iPSCs), 3) Use for screening compounds, antibodies, proteins, peptides and others in developing pharmaceuticals (including diagnostic agents) for human and/or animal use (including use of the differentiated cells from iPSCs), and 4) Transfer to a third party (including transfer of the differentiated cells from iPSCs). A patent license to use of iPSCs generated by this product and the use of the differentiated cells from the iPSCs for screening compounds may also be granted from Takara Bio Inc.
C006	For Not-For-Profit Entities, the purchase of this product grants to the purchaser, a non-exclusive, non-transferable, non-sublicensable and limited license to use this product for internal, non-commercial, scientific research use only. The license specifically excludes the right to sell or otherwise transfer this product, its components or derivatives thereof to a third party, regardless of whether or not compensation is received. The license does not grant any right for the purchaser to use this product or its components in humans for any purposes including but not limited to diagnostics and/or therapeutics, or otherwise clinical trials. Purchasers wishing to use this product for purposes other than internal research use should contact us. No express or implied license is granted to the purchaser. For-Profit Entities in North America wishing to purchase this product are required to submit a completed copy of the Human iPS Cell Line license agreement to us. For details please contact licensing@takarabio.com A copy of the Cellartis® Human iPS Cell Line 7 (ChiPSC7) Kit product License Agreement can be found by clicking here.

Cellartis human iPS cell line 7 is maintained and frozen in DEF-CS medium (sold as part of the Cellartis DEF-CS Culture System). It is recommended to thaw the cells in the provided Cellartis DEF-CS 100 Culture System, a defined culture system for growth of undifferentiated human iPS cells. The Cellartis DEF-CS 100 Culture System includes basal medium, additives and coating compound.

Notice to purchaser

Components

Overview

Cell lines were created by reprogramming human skin fibroblasts using defective polycistronic retrovirus technology to deliver OCT-4, SOX2, KLF4, and c-Myc
Cell lines are extensively analyzed for purity and stem-cell characteristics, including recovery after thawing, absence of mycoplasma and bacteria, expression of stem cell-specific markers (OCT-4, NANOG, SSEA-3, SSEA-4, TRA-1-60, TRA-1-81), absence of differentiation markers (Beta-3 tubulin, FOXA2, ASMA), and expected karyotype
Optimized for culture with the Cellartis DEF-CS Culture System
Suitable for all major applications; cells can form derivatives of all three germ layers when differentiated
Kits include the Cellartis DEF-CS 100 Culture System

Characteristics of Cellartis human iPS cells
Name	Age of donor (years)	Confirmed differentiation	Commercially available differentiated cells	Karyotype (from banked cells)	HLA typification
Cellartis Human iPS Cell Line 7 (ChiPSC7)	20	Hepatocytes Beta cells Cardiomyocytes Endothelial cells	N/A	46, XX	HLA-A03:01 HLA-B07:02, HLA‑B35:01 HLA-C04:01, HLA-C07:02 HLA‑DRB101:01, HLA‑DRB115:01 HLA‑DQB105:01, HLA-DQB106:02 HLA-DPB104:01, HLA‑DPB1*04:02
Cellartis Human iPS Cell Line 12 (ChiPSC12)	24	Hepatocytes Beta cells Cardiomyocytes Neural progenitors Endothelial cells	Cellartis Enhanced hiPS-HEP v2 (from ChiPSC12) Kit Cellartis hiPS Beta Cells (from ChiPSC12) Kit	46, XY	HLA-A01:01 HLA-B08:01, HLA-B37:01 HLA-C06:02, HLA-C07:01 HLA‑DRB103:01, HLA-DRB111:04 HLA-DQB102:01, HLA-DQB103:01 HLA-DPB101:01, HLA-DPB1*04:01
Cellartis Human iPS Cell Line 18 (ChiPSC18)	32	Hepatocytes Cardiomyocytes Neural progenitors Intestinal epithelial cells	Cellartis Enhanced hiPS-HEP v2 (from ChiPSC18) Kit Cellartis Definitive Endoderm Cells (from ChiPSC18) Cellartis Intestinal Epithelial Cells (from ChiPSC18) Kit	46, XY	HLA-A23:01 HLA-B07:02, HLA-B49:01 HLA-C07:01, HLA-C07:02 HLA-DRB104:06, HLA-DRB107:01 HLA‑DQB102:02, HLA-DQB104:02 HLA-DPB103:01, HLA-DPB1*04:01
Cellartis Human iPS Cell Line 22 (ChiPSC22)	32	Hepatocytes Beta cells Cardiomyocytes Neural progenitors Endothelial cells	Cellartis Enhanced hiPS-HEP v2 (from ChiPSC22) Kit Cellartis hiPS Beta Cells (from ChiPSC22) Kit Cellartis Cardiomyocytes (from ChiPSC22) Kit	46, XY	HLA-A02:01 HLA-B07:02, HLA-B40:01 HLA-C03:04, HLA-C07:02 HLA-DRB113:02, HLA-DRB114:01 HLA-DQB105:03, HLA-DQB106:04 HLA-DPB103:01, HLA-DPB1*04:01

More Information

Source

Cell lines were derived from human skin fibroblasts of different donors. Please refer to the Certificate of Analysis in the Documents tab for cell line-specific information, such as donor information and karyotype.

Additional product information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

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FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. © 2024 Takara Bio Inc. All Rights Reserved. All trademarks are the property of Takara Bio Inc. or its affiliate(s) in the U.S. and/or other countries or their respective owners. Certain trademarks may not be registered in all jurisdictions. Additional product, intellectual property, and restricted use information is available at takarabio.com.

Human induced pluripotent stem cells

Notice to purchaser

Characteristics of Cellartis human iPS cells

Notice to purchaser

Characteristics of Cellartis human iPS cells

Notice to purchaser

Characteristics of Cellartis human iPS cells

Notice to purchaser

Characteristics of Cellartis human iPS cells

Overview

More Information

Source

Additional product information