Antibody selection guide: stem cell and differentiated cell markers
Pluripotent cell markers
Identify stemness and characterize your pluripotent cells using antibodies against a variety of stem cell markers. The antibodies below can be used to characterize pluripotency and purify embryonic stem (ES) and induced pluripotent stem (iPS) cell lines from contaminating feeder cells and non-stem cells.
| Target | Application | Species reactivity | Product |
|---|---|---|---|
| OCT4, a transcription factor involved in the self-renewal of ES cells | Characterize human pluripotent stem cells | Human | Oct4 (Human), Monoclonal (Cat. # M221) |
| SOX-2, a transcription factor required to maintain pluripotency in undifferentiated ES cells | Characterize human pluripotent stem cells | Human | Sox2 (Human), Monoclonal (Cat. # M223) |
| LIN-28, an ES cell marker | Characterize human pluripotent stem cells | Human | Lin28 (Human), Monoclonal (Cat. # M222) |
| Surface epitope on human ES and iPS cells | Characterize human pluripotent stem cells Separate human ES and iPS cells from feeder cells |
Human | hES-Cellect* (Cat. # Y20010) |
| Surface epitope on human and mouse ES and iPS cells | Characterize pluripotent stem cells | Human, mouse |
ES-Cellect* (Cat. # Y20011) |
*This product may not be available in all countries. Please check with your local sales representative.
Differentiated cell markers
Identify and characterize differentiated cell types derived from embryonic and induced pluripotent stem cells. The antibodies below can be used to monitor differentiation, identify and sort differentiated cells, and track transplanted stem cells.
| Target | Application | Species reactivity | Product |
|---|---|---|---|
| Nuclear protein expressed in a variety of human tissues, including brain | Detect the migration, engraftment, and differentiation of human cells transplanted into rodents | Human | STEM101 (Cat. # Y40400) |
| Cytoplasmic protein expressed in a variety of tissues including brain, liver, and pancreas | Detect the migration, engraftment, and differentiation of human cells transplanted into rodents | Human | STEM121 (Cat. # Y40410) |
| Glial fibrillary acidic protein (GFAP) | Identify astrocytes derived from human neural stem cells transplanted into rodents | Human | STEM123 (Cat. # Y40420) |
| Human fibroblasts | Characterize and purify human feeder cells Distinguish nonreprogrammed fibroblasts |
Human | hFF-Cellect* (Cat. # Y20012) |
*This product may not be available in all countries. Please check with your local sales representative.
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