Coming soon! SMART-Seq mRNA Long Read
Unlock full-length RNA isoforms and alternative splicing from critical, low-input samples
Introducing the first commercial sequencing solution for generating full-length cDNA fragments from ultra-low inputs. SMART-Seq mRNA Long Read enables reliable long-read (LR) sequencing to capture full-length transcripts up to 10 kb in length from a single cell (~10 pg total RNA), up to 1,000 cells (or 100 ng total RNA). The streamlined workflow supports multiplexing of up to 96 samples, to deliver efficient long-read library preparation and sequencing on the Oxford Nanopore Technology platform.
View the data in our poster and sign up to be notified when SMART-Seq mRNA Long Read is released.
Featured poster
Enabling long-read mRNA-seq for biomarker discovery using limited clinical sample inputs
With this poster, Dr. Yue Yun presented data from a new long-read RNA sequencing product that enables full-length RNA sequencing from single cells (~10 pg) up to 100 ng total RNA. With a 10 ng total RNA input, we demonstrate the ability to reliably sequence at an average length (N50) of 2 kb and detect full-length transcripts as long as 10 kb. Performance at the single-cell level is substantially better than existing single-cell LR-RNA-seq methods. Furthermore, our data provides a more complete picture of isoform-specific changes compared to other commercially available technologies. With the ability to process up to 96 samples at a time, this technology will enable the processing of rare or valuable samples to uncover novel biomarkers beyond gene expression.
Sign up to be notified when SMART-Seq mRNA Long Read is released.
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